Genetic Ablation of STE20-Type Kinase MST4 Does Not Alleviate Diet-Induced MASLD Susceptibility in Mice

Genetic Ablation of STE20-Type Kinase MST4 Does Not Alleviate Diet-Induced MASLD Susceptibility in Mice

Metabolic dysfunction-associated steatotic liver disease (MASLD) and its advanced subtype, metabolic dysfunction-associated steatohepatitis (MASH), have emerged as the most common chronic liver disease worldwide, yet there is no targeted pharmacotherapy presently available. This study aimed to inves...

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Bibliographic Details
Main Authors: Mara Caputo, Emma Andersson, Ying Xia, Wei Hou, Emmelie Cansby, Max Erikson, Dan Emil Lind, Bengt Hallberg, Manoj Amrutkar, Margit Mahlapuu
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
MST4
metabolic dysfunction-associated steatotic liver disease
metabolic dysfunction-associated steatohepatitis
liver lipid metabolism
intrahepatocellular lipid droplets
Online Access:https://www.mdpi.com/1422-0067/25/4/2446

Internet

https://www.mdpi.com/1422-0067/25/4/2446

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