A Nanoparticle Delivery of Plasmid Encoding Hepatocyte Growth Factor for Gene Therapy of Silicosis in Mice

Purpose: Silicosis is a serious occupational disease that is characterized by pulmonary infiltrates and fibrosis and is often refractory to current treatments. New therapeutic strategies for silicosis are needed. Hepatocyte growth factor (HGF) is a latent anti-inflammatory and anti-fibrotic growth f...

Full description

Bibliographic Details
Main Authors: Haiying Duan, Peng Gao, Xiaochen Cheng, Yuxin Lu, Chunsheng Hu, Xuefeng Zhu, Xiaoying Wang, Dujuan Li, Fengjun Xiao, Li Du, Yunmei Liu, Qinglin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/32218