The NFATc1/P2X7 receptor relationship in human intervertebral disc cells

The NFATc1/P2X7 receptor relationship in human intervertebral disc cells

A comprehensive understanding of the molecules that play key roles in the physiological and pathological homeostasis of the human intervertebral disc (IVD) remains challenging, as does the development of new therapeutic treatments. We recently found a positive correlation between IVD degeneration (I...

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Bibliographic Details
Main Authors: Maria Pina Notarangelo, Letizia Penolazzi, Elisabetta Lambertini, Simonetta Falzoni, Pasquale De Bonis, Cristina Capanni, Francesco Di Virgilio, Roberta Piva
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
intervertebral disc cells
P2X7 purinergic receptor
NFATc1 transcription factor
hypoxia-inducible factor-1α
proximity ligation assay
lamin A/C
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1368318/full

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https://www.frontiersin.org/articles/10.3389/fcell.2024.1368318/full

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