Ovarian steroids modulate mRNA expression of ECM associated genes and collagen deposition induced by TGF β1 in equine endometrium in vitro

Abstract Equine endometrosis is a major cause of infertility in mares and is characterized by degenerative, functional and fibrotic changes in the endometrium with increased collagen (COL) deposition. Transforming growth factor (TGF)-β1 is one of the major pro-fibrotic factors involved in the excess...

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Bibliographic Details
Main Authors: Amaral Ana, Sadowska Agnieszka, Cerveira-Pinto Marta, Kordowitzki Pawel, Skarzynski Dariusz, Ferreira-Dias Graça, Anna Szóstek-Mioduchowska
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-84250-1