Radiolabelled FGF-2 for Imaging Activated Fibroblasts in the Tumor Micro-Environment

Radiolabelled FGF-2 for Imaging Activated Fibroblasts in the Tumor Micro-Environment

Tumor associated fibroblasts (TAFs) play a key role in tumor growth and metastatization. TAFs overexpress different biomarkers that are usually expressed at low levels in physiological conditions. Among them are the fibroblast growth factor receptors (FGFRs) that bind the fibroblast growth factors (...

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Bibliographic Details
Main Authors: Valeria Bentivoglio, Filippo Galli, Michela Varani, Danilo Ranieri, Pallavi Nayak, Annunziata D’Elia, Andrea Soluri, Roberto Massari, Chiara Lauri, Alberto Signore
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Biomolecules
Subjects:
fibroblasts
tumor microenvironment
cancer imaging
nuclear medicine
Online Access:https://www.mdpi.com/2218-273X/14/4/491

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https://www.mdpi.com/2218-273X/14/4/491

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