Keratinocytes can modulate and directly initiate nociceptive responses

How thermal, mechanical and chemical stimuli applied to the skin are transduced into signals transmitted by peripheral neurons to the CNS is an area of intense study. Several studies indicate that transduction mechanisms are intrinsic to cutaneous neurons and that epidermal keratinocytes only modula...

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Bibliographic Details
Main Authors: Kyle M Baumbauer, Jennifer J DeBerry, Peter C Adelman, Richard H Miller, Junichi Hachisuka, Kuan Hsien Lee, Sarah E Ross, H Richard Koerber, Brian M Davis, Kathryn M Albers
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/09674