Capsomer vaccines protect mice from vaginal challenge with human papillomavirus.

Capsomer vaccines protect mice from vaginal challenge with human papillomavirus.

Capsomers were produced in bacteria as glutathione-S-transferase (GST) fusion proteins with human papillomavirus type 16 L1 lacking the first nine and final 29 residues (GST-HPV16L1Δ) alone or linked with residues 13-47 of HPV18, HPV31 and HPV45 L2 in tandem (GST-HPV16L1Δ-L2x3). Subcutaneous immuniz...

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Bibliographic Details
Main Authors: Wai-Hong Wu, Elizabeth Gersch, Kihyuck Kwak, Subhashini Jagu, Balasubramanyam Karanam, Warner K Huh, Robert L Garcea, Richard B S Roden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206079?pdf=render

Internet

http://europepmc.org/articles/PMC3206079?pdf=render

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