An Optogenetic‐Controlled Cell Reprogramming System for Driving Cell Fate and Light‐Responsive Chimeric Mice

Abstract Pluripotent stem cells (PSCs) hold great promise for cell‐based therapies, disease modeling, and drug discovery. Classic somatic cell reprogramming to generate induced pluripotent stem cells (iPSCs) is often achieved based on overexpression of transcription factors (TFs). However, this proc...

Full description

Bibliographic Details
Main Authors: Meiyan Wang, Yuanxiao Liu, Ziwei Wang, Longliang Qiao, Xiaoding Ma, Lingfeng Hu, Deqiang Kong, Yuan Wang, Haifeng Ye
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202202858