Design and execution of a verification, validation, and uncertainty quantification plan for a numerical model of left ventricular flow after LVAD implantation.

<h4>Background</h4>Left ventricular assist devices (LVADs) are implantable pumps that act as a life support therapy for patients with severe heart failure. Despite improving the survival rate, LVAD therapy can carry major complications. Particularly, the flow distortion introduced by the...

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Bibliographic Details
Main Authors: Alfonso Santiago, Constantine Butakoff, Beatriz Eguzkitza, Richard A Gray, Karen May-Newman, Pras Pathmanathan, Vi Vu, Mariano Vázquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010141