RAR-Dependent and RAR-Independent RXR Signaling in Stem-like Glioma Cells

RAR-Dependent and RAR-Independent RXR Signaling in Stem-like Glioma Cells

Retinoic acid (RA) exerts pleiotropic effects during neural development and regulates homeostasis in the adult human brain. The RA signal may be transduced through RXR (retinoid-X receptor)-non-permissive RA receptor/RXR heterodimers or through RXR-permissive RXR heterodimers. The significance of RA...

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Bibliographic Details
Main Authors: Amanda Dabrock, Natalie Ernesti, Florian Will, Manaf Rana, Nadja Leinung, Phillip Ehrich, Volker Tronnier, Christina Zechel
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
malignant glioma
retinoic acid receptors
retinoid-X receptor
synthetic retinoids
CRISPR/Cas9 editing
Online Access:https://www.mdpi.com/1422-0067/24/22/16466

Internet

https://www.mdpi.com/1422-0067/24/22/16466

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