Interleukin-17 Reduces βENaC via MAPK Signaling in Vascular Smooth Muscle Cells
Degenerin proteins, such as the beta epithelial Na<sup>+</sup> channel (βENaC), are essential in the intracellular signaling of pressure-induced constriction, an important vascular smooth muscle cell (VSMC) function. While certain cytokines reduce ENaC protein in epithelial tissue, it is...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/8/2953 |