Budesonide, but not dexamethasone, blunted the response of aldosterone to renin elevation by suppressing angiotensin converting enzyme upon high-altitude exposure

Introduction: Inhaled budesonide is a novel approach to prevent acute mountain sickness (AMS). However, its mechanism is not completely understood. We aimed to investigate the effects of budesonide and dexamethasone on renin–angiotensin–aldosterone system in AMS prevention. Materials and methods: Da...

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Bibliographic Details
Main Authors: Hui-Jie Li, Cheng-Rong Zheng, Guo-Zhu Chen, Jun Qin, Ji-Hang Zhang, Jie Yu, En-Hao Zhang, Lan Huang
Format: Article
Language:English
Published: SAGE Publications 2016-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320316653867