Primitive Neural Stem Cells in the Adult Mammalian Brain Give Rise to GFAP-Expressing Neural Stem Cells

Adult forebrain definitive neural stem cells (NSCs) comprise a subpopulation of GFAP-expressing subependymal cells that arise from embryonic fibroblast growth factor (FGF)-dependent NSCs that are first isolated from the developing brain at E8.5. Embryonic FGF-dependent NSCs are derived from leukemia...

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Bibliographic Details
Main Authors: Nadia Sachewsky, Rachel Leeder, Wenjun Xu, Keeley L. Rose, Fenggang Yu, Derek van der Kooy, Cindi M. Morshead
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114001155