NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development

NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development

In recent years, cell-based immunotherapies have demonstrated promising results in the treatment of cancer. Chimeric antigen receptors (CARs) arm effector cells with a weapon for targeting tumor antigens, licensing engineered cells to recognize and kill cancer cells. The quality of the CAR-antigen i...

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Bibliographic Details
Main Authors: Ali Bashiri Dezfouli, Mina Yazdi, Alan Graham Pockley, Mohammad Khosravi, Sebastian Kobold, Ernst Wagner, Gabriele Multhoff
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
immunotherapy
natural killer cells
chimeric antigen receptor
tumor antigen
gene delivery
Online Access:https://www.mdpi.com/2073-4409/10/12/3390

Internet

https://www.mdpi.com/2073-4409/10/12/3390

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