Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron

Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron

The different segments of the nephron and glomerulus in the kidney balance the processes of water homeostasis, solute recovery, blood filtration, and metabolite excretion. When segment function is disrupted, a range of pathological features are presented. Little is known about nephron patterning dur...

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Bibliographic Details
Main Authors: Nils O Lindström, Melanie L Lawrence, Sally F Burn, Jeanette A Johansson, Elvira RM Bakker, Rachel A Ridgway, C-Hong Chang, Michele J Karolak, Leif Oxburgh, Denis J Headon, Owen J Sansom, Ron Smits, Jamie A Davies, Peter Hohenstein
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-02-01
Series:eLife
Subjects:
kidney development
patterning
beta-catenin
PI3K
Notch
BMP
Online Access:https://elifesciences.org/articles/04000

Internet

https://elifesciences.org/articles/04000

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