Orally administered intelligent self-ablating nanoparticles: a new approach to improve drug cellular uptake and intestinal absorption

Orally administered intelligent self-ablating nanoparticles: a new approach to improve drug cellular uptake and intestinal absorption

Oral drug delivery to treat diabetes is being increasingly researched. The mucus and the epithelial cell layers hinder drug delivery. We designed a self-ablating nanoparticle to achieve smart oral delivery to overcome the gastrointestinal barrier. We used the zwitterionic dilauroyl phosphatidylcholi...

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Bibliographic Details
Main Authors: Yanzi Liang, Ruihuan Ding, Huihui Wang, Lanze Liu, Jibiao He, Yuping Tao, Zhenyu Zhao, Jie Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
oral drug delivery
zwitterionic materials
self-ablating nanoparticle
cellular uptake
intestinal absorption
Online Access:http://dx.doi.org/10.1080/10717544.2021.2023704

Internet

http://dx.doi.org/10.1080/10717544.2021.2023704

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