MicroRNA-142-3p Inhibits Tumorigenesis of Colorectal Cancer via Suppressing the Activation of Wnt Signaling by Directly Targeting to β-Catenin

MicroRNA-142-3p Inhibits Tumorigenesis of Colorectal Cancer via Suppressing the Activation of Wnt Signaling by Directly Targeting to β-Catenin

BackgroundAltered expression profile of microRNAs (miRNAs) was reported to be associated with colorectal cancer (CRC). The aims of this study are to identify the changed miRNAs in the plasma of CRC patients and explore the underlying mechanism of these miRNAs during tumorigenesis.MethodsPlasma miRNA...

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Bibliographic Details
Main Authors: Peng Liu, Fuao Cao, Jinke Sui, Yonggang Hong, Qizhi Liu, XianHua Gao, Haifeng Gong, Liqiang Hao, Zheng Lou, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
microRNA-142-3p
colorectal cancer
Wnt signaling
β-catenin
CTNNB1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.552944/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.552944/full

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