Lineage-specific co-evolution of the Egf receptor/ligand signaling system
<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand system contributes to many human malignancies. Consis...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-01-01
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Series: | BMC Evolutionary Biology |
Online Access: | http://www.biomedcentral.com/1471-2148/10/27 |