Lineage-specific co-evolution of the Egf receptor/ligand signaling system

<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand system contributes to many human malignancies. Consis...

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Bibliographic Details
Main Authors: Meierjohann Svenja, Walter Ronald B, Braasch Ingo, Laisney Juliette AGC, Schartl Manfred
Format: Article
Language:English
Published: BMC 2010-01-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/10/27