Familial co-aggregation and shared genetics of cardiometabolic disorders and traits: data from the multi-generational Lifelines Cohort Study

Familial co-aggregation and shared genetics of cardiometabolic disorders and traits: data from the multi-generational Lifelines Cohort Study

Abstract Background It is unclear to what extent genetics explain the familial clustering and the co-occurrence of distinct cardiometabolic disorders in the general population. We therefore aimed to quantify the familial (co-)aggregation of various cardiometabolic disorders and to estimate the herit...

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Bibliographic Details
Main Authors: Rima D. Triatin, Zekai Chen, Alireza Ani, Rujia Wang, Catharina A. Hartman, Ilja M. Nolte, Chris H. L. Thio, Harold Snieder
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cardiovascular Diabetology
Subjects:
Cardiometabolic disorders
Cardiometabolic traits
Familial (co-)aggregation
Genetic correlation
Heritability
Online Access:https://doi.org/10.1186/s12933-023-02017-w

Internet

https://doi.org/10.1186/s12933-023-02017-w

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