Long-term stimulation with alternating electric fields modulates the differentiation and mineralization of human pre-osteoblasts

Biophysical stimulation by electric fields can promote bone formation in bone defects of critical size. Even though, long-term effects of alternating electric fields on the differentiation of osteoblasts are not fully understood. Human pre-osteoblasts were stimulated over 31 days to gain more inform...

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Bibliographic Details
Main Authors: Franziska Sahm, Vivica Freiin Grote, Julius Zimmermann, Fiete Haack, Adelinde M. Uhrmacher, Ursula van Rienen, Rainer Bader, Rainer Detsch, Anika Jonitz-Heincke
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.965181/full