Construction and Validation of a Tumor Microenvironment-Based Scoring System to Evaluate Prognosis and Response to Immune Checkpoint Inhibitor Therapy in Lung Adenocarcinoma Patients

Construction and Validation of a Tumor Microenvironment-Based Scoring System to Evaluate Prognosis and Response to Immune Checkpoint Inhibitor Therapy in Lung Adenocarcinoma Patients

Background: Lung cancer is among the most dangerous malignant tumors to human health. Lung adenocarcinoma (LUAD) accounts for about 40% of all lung cancers. Accumulating evidence suggests that the tumor microenvironment (TME) is a crucial regulator of carcinogenesis and therapeutic efficacy in LUAD....

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Bibliographic Details
Main Authors: Pinzheng Huang, Linfeng Xu, Mingming Jin, Lixi Li, Yizhong Ke, Min Zhang, Kairui Zhang, Kongyao Lu, Gang Huang
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Genes
Subjects:
lung adenocarcinoma
tumor microenvironment
prognostic stratification
immune checkpoint inhibitor therapeutic response evaluation
TIDE score
Online Access:https://www.mdpi.com/2073-4425/13/6/951

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https://www.mdpi.com/2073-4425/13/6/951

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