The plot thickens: OTULIN regulation in cell death

We recently demonstrated that post-translational modifications of the OTU deubiquitinase with linear linkage specificity (OTULIN) regulate its function in cell death. OTULIN hyper-phosphorylation promotes necroptosis by locking ring finger protein 31 (RNF31, also known as HOIP) away from the cylindr...

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Bibliographic Details
Main Authors: Todd Douglas, Maya Saleh
Format: Article
Language:English
Published: Taylor & Francis Group 2020-07-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1740541