TPG-functionalized PLGA/PCL nanofiber membrane facilitates periodontal tissue regeneration by modulating macrophages polarization via suppressing PI3K/AKT and NF-κB signaling pathways

TPG-functionalized PLGA/PCL nanofiber membrane facilitates periodontal tissue regeneration by modulating macrophages polarization via suppressing PI3K/AKT and NF-κB signaling pathways

Traditional fibrous membranes employed in guided tissue regeneration (GTR) in the treatment of periodontitis have limitations of bioactive and immunomodulatory properties. We fabricated a novel nTPG/PLGA/PCL fibrous membrane by electrospinning which exhibit excellent hydrophilicity, mechanical prope...

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Bibliographic Details
Main Authors: Xiang Han, Feiyang Wang, Yuzhuo Ma, Xuerong Lv, Kewei Zhang, Yue Wang, Ke Yan, Youmin Mei, Xiaoqian Wang
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Materials Today Bio
Subjects:
Periodontal tissue regeneration
TPG
Electrospinning
Macrophages
Immune microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424000954

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http://www.sciencedirect.com/science/article/pii/S2590006424000954

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