STAT6 Deficiency Attenuates Myeloid Fibroblast Activation and Macrophage Polarization in Experimental Folic Acid Nephropathy

STAT6 Deficiency Attenuates Myeloid Fibroblast Activation and Macrophage Polarization in Experimental Folic Acid Nephropathy

Renal fibrosis is a pathologic feature of chronic kidney disease, which can lead to end-stage kidney disease. Myeloid fibroblasts play a central role in the pathogenesis of renal fibrosis. However, the molecular mechanisms pertaining to myeloid fibroblast activation remain to be elucidated. In the p...

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Bibliographic Details
Main Authors: Baihai Jiao, Changlong An, Hao Du, Melanie Tran, Penghua Wang, Dong Zhou, Yanlin Wang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
STAT6
macrophage polarization
fibroblasts
fibrosis
chronic kidney disease
Online Access:https://www.mdpi.com/2073-4409/10/11/3057

Internet

https://www.mdpi.com/2073-4409/10/11/3057

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