Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction.

Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction.

Serum and glucocorticoid inducible kinase 1 (SGK1) plays a pivotal role in early angiogenesis during embryonic development. In this study, we sought to define the SGK1 downstream signalling pathways in the adult heart and to elucidate their role in cardiac neo-angiogenesis and wound healing after my...

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Bibliographic Details
Main Authors: Elham Zarrinpashneh, Tommaso Poggioli, Padmini Sarathchandra, Jonas Lexow, Laurent Monassier, Cesare Terracciano, Florian Lang, Federico Damilano, Jessica Q Zhou, Anthony Rosenzweig, Nadia Rosenthal, Maria Paola Santini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827188?pdf=render

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http://europepmc.org/articles/PMC3827188?pdf=render

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