Insights Into Persistent HIV-1 Infection and Functional Cure: Novel Capabilities and Strategies

Insights Into Persistent HIV-1 Infection and Functional Cure: Novel Capabilities and Strategies

Although HIV-1 replication can be efficiently suppressed to undetectable levels in peripheral blood by combination antiretroviral therapy (cART), lifelong medication is still required in people living with HIV (PLWH). Life expectancies have been extended by cART, but age-related comorbidities have i...

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Bibliographic Details
Main Authors: Tram M. Ta, Sajjaf Malik, Elizabeth M. Anderson, Amber D. Jones, Jocelyn Perchik, Maryann Freylikh, Luca Sardo, Zackary A. Klase, Taisuke Izumi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
human immunodeficiency virus (HIV)
functional HIV cure
HIV latency
HIV persistence
kick-and-kill strategy
Block-and-Lock strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.862270/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.862270/full

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