Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells

Transdifferentiation, where differentiated cells are reprogrammed into another lineage without going through an intermediate proliferative stem cell-like stage, is the next frontier of regenerative medicine. Wernig et al. first described the direct conversion of fibroblasts into functional induced n...

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Bibliographic Details
Main Authors: Andrew F Adler, Christopher L Grigsby, Karina Kulangara, Hong Wang, Ryohei Yasuda, Kam W Leong
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300890