Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells
Transdifferentiation, where differentiated cells are reprogrammed into another lineage without going through an intermediate proliferative stem cell-like stage, is the next frontier of regenerative medicine. Wernig et al. first described the direct conversion of fibroblasts into functional induced n...
Main Authors: | Andrew F Adler, Christopher L Grigsby, Karina Kulangara, Hong Wang, Ryohei Yasuda, Kam W Leong |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-01-01
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Series: | Molecular Therapy: Nucleic Acids |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253116300890 |
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