Multi‐level metabolic engineering of Escherichia coli for high‐titer biosynthesis of 2′‐fucosyllactose and 3‐fucosyllactose

Abstract Fucosyllactoses (FL), including 2′‐fucosyllactose (2′‐FL) and 3‐fucosyllactose (3‐FL), have garnered considerable interest for their value in newborn formula and pharmaceuticals. In this study, an engineered Escherichia coli was developed for high‐titer FL biosynthesis by introducing multi‐...

Full description

Bibliographic Details
Main Authors: Mengli Li, Chenchen Li, Yejiao Luo, Miaomiao Hu, Zhu Liu, Tao Zhang
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.14152