Suppressor of cytokine signaling-3 expression and its regulation in relation to inflammation in Chronic Obstructive Pulmonary Disease

Suppressor of cytokine signaling-3 expression and its regulation in relation to inflammation in Chronic Obstructive Pulmonary Disease

BackgroundThe family of Suppressor of Cytokine Signaling (SOCS) acts as a controller of the duration and intensity of cytokine function by negatively regulating the JAK-STAT signaling pathway. SOCS’ role in inflammatory diseases in animal models is well demonstrated. However, its role in the develop...

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Main Authors: Mariaenrica Tinè, Elisabetta Balestro, Sara Carpi, Tommaso Neri, Davide Biondini, Maria Conti, Alvise Casara, Nicol Bernardinello, Elisabetta Cocconcelli, Graziella Turato, Simonetta Baraldo, Alessandro Celi, Paolo Spagnolo, Manuel G. Cosio, Marina Saetta, Erica Bazzan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
socs3
extracellular vesicles
COPD
miRNA
human BAL
alveolar macrophages
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1320077/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1320077/full

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