First case of near haploid philadelphia negative B-Cell acute lymphoblastic leukaemia relapsing as acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation

First case of near haploid philadelphia negative B-Cell acute lymphoblastic leukaemia relapsing as acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation

Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia demonstrating near haploid karyotype and abnormal TP53 expression at diagnosis, who relapsed with lineage switch as Acute Monocytic Leukemia post allogeneic stem cell transplantation. Molecular analys...

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Bibliographic Details
Main Authors: Claire Horgan, Charalampos Kartsios, Emmanouil Nikolousis, Paneesha Shankara, Bhuvan Kishore, Richard Lovell, Vidhya Murthy, Zbigniew Rudzki, Sara Dyer, Pam Holtom, Gillian Thompson, Maria Kaparou, Evgenia Xenou, Rebecca Lloyd, Indrani Venkatadasari, Alexandros Georgios Kanellopoulos
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Leukemia Research Reports
Subjects:
Acute lymphoblastic leukemia
Acute myeloid leukemia
Lineage switch
Allogeneic stem cell transplantation
Inotuzumab Ozogamicin
Near-Haploidy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048920300194

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http://www.sciencedirect.com/science/article/pii/S2213048920300194

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