The influence of tissue pH and RNA integrity number on gene expression of human postmortem brain

The influence of tissue pH and RNA integrity number on gene expression of human postmortem brain

BackgroundEvaluating and controlling confounders are necessary when investigating molecular pathogenesis using human postmortem brain tissue. Particularly, tissue pH and RNA integrity number (RIN) are valuable indicators for controlling confounders. However, the influences of these indicators on the...

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Bibliographic Details
Main Authors: Kazusa Miyahara, Mizuki Hino, Zhiqian Yu, Chiaki Ono, Atsuko Nagaoka, Masataka Hatano, Risa Shishido, Hirooki Yabe, Hiroaki Tomita, Yasuto Kunii
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Psychiatry
Subjects:
schizophrenia
postmortem brain
microarray
pH
RNA integrity number
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1156524/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1156524/full

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