CRISPR/Cas9-mediated generation of a Plac8 knockout mouse model

Abstract Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various diseases, including cancers, obesity, and innate immune deficiency. Here, we generated a Plac8 knockout...

Full description

Bibliographic Details
Main Authors: HyunJeong Lee, Joo-Il Kim, Jin-Sung Park, Jae-il Roh, Jaehoon Lee, Byeong-Cheol Kang, Han-Woong Lee
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Laboratory Animal Research
Subjects:
Online Access:http://link.springer.com/article/10.5625/lar.2018.34.4.279