CRISPR/Cas9-mediated generation of a Plac8 knockout mouse model
Abstract Placenta specific 8 (PLAC8, also known as ONZIN) is a multi-functional protein that is highly expressed in the intestine, lung, spleen, and innate immune cells, and is involved in various diseases, including cancers, obesity, and innate immune deficiency. Here, we generated a Plac8 knockout...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-12-01
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Series: | Laboratory Animal Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.5625/lar.2018.34.4.279 |