A Diastereoselective Synthesis of Dispiro[oxindole-cyclohexanone]pyrrolidines by 1,3-Dipolar Cycloaddition

A Diastereoselective Synthesis of Dispiro[oxindole-cyclohexanone]pyrrolidines by 1,3-Dipolar Cycloaddition

For the first time, arylmethylidene cyclohexanones that are non-symmetrical due to the presence of peripheral substituents were studied in 1,3-dipolar cycloaddition reactions. It is shown that the interaction with the azomethine ylide generated from sarcosine proceeds regio- and diastereoselectively...

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Bibliographic Details
Main Authors: Alexander Anis’kov, Irina Klochkova, Roman Tumskiy, Alevtina Yegorova
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
spiro[indoline-3,2′-pyrrolidin]-2-one
azomethine ylides
unsaturated ketones
1,3-dipolar cycloaddition
sarcosine
Online Access:https://www.mdpi.com/1420-3049/22/12/2134

Internet

https://www.mdpi.com/1420-3049/22/12/2134

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