Early-life hyperoxia-induced Flt3L drives neonatal lung dendritic cell expansion and proinflammatory responses

Early-life hyperoxia-induced Flt3L drives neonatal lung dendritic cell expansion and proinflammatory responses

Premature infants with chronic lung disease, bronchopulmonary dysplasia (BPD), develop recurrent cough and wheezing following respiratory viral infections. The mechanisms driving the chronic respiratory symptoms are ill-defined. We have shown that hyperoxic exposure of neonatal mice (a model of BPD)...

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Bibliographic Details
Main Authors: Tracy X. Cui, Alexander E. Brady, Ying-Jian Zhang, Christina T. Fulton, Adam M. Goldsmith, Antonia P. Popova
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
prematurity
bronchopulmonary dysplasia (BPD)
hyperoxia
dendritic cells
Flt3L
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116675/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116675/full

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