Early-life hyperoxia-induced Flt3L drives neonatal lung dendritic cell expansion and proinflammatory responses

Premature infants with chronic lung disease, bronchopulmonary dysplasia (BPD), develop recurrent cough and wheezing following respiratory viral infections. The mechanisms driving the chronic respiratory symptoms are ill-defined. We have shown that hyperoxic exposure of neonatal mice (a model of BPD)...

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Bibliografske podrobnosti
Main Authors: Tracy X. Cui, Alexander E. Brady, Ying-Jian Zhang, Christina T. Fulton, Adam M. Goldsmith, Antonia P. Popova
Format: Article
Jezik:English
Izdano: Frontiers Media S.A. 2023-02-01
Serija:Frontiers in Immunology
Teme:
Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116675/full