The effects of synthetic immunostimulator polyoxidonium on methotrexate treatment in rats with adjuvant arthritis

The purpose of this study was to evaluate the effect of polyoxidonium(POX) on prophylactic treatment of adjuvant arthritis (AA)with methotrexate (MTX) in rats. Groups of rats with AA weretreated with methotrexate (1 mg/kg/week), polyoxidonium(0.1 mg/kg) or their combination for a period of 28 days f...

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Bibliographic Details
Main Authors: Jozef Rovenský, Karol Švik, Stanislava Blažíčková, Mária Stančíková
Format: Article
Language:English
Published: Termedia Publishing House 2011-12-01
Series:Rheumatology
Subjects:
Online Access:http://www.termedia.pl/Artykul-oryginalny-Wplyw-syntetycznego-immunostymulatora-polioksydonium-na-leczenie-metotreksatem-stosowane-u-szczurow-z-adiuwantowym-zapaleniem-stawow,18,17887,1,0.html