Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase.

Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase.

During meiosis, recombination between homologous chromosomes (homologs) generates crossovers that promote proper segregation at the first meiotic division. Recombination is initiated by Spo11-catalyzed DNA double strand breaks (DSBs). 5' end resection of the DSBs creates 3' single strand t...

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Bibliographic Details
Main Authors: Andrew Ziesel, Qixuan Weng, Jasvinder S Ahuja, Abhishek Bhattacharya, Raunak Dutta, Evan Cheng, G Valentin Börner, Michael Lichten, Nancy M Hollingsworth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010407

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https://doi.org/10.1371/journal.pgen.1010407

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