Mutant ATRX: pathogenesis of ATRX syndrome and cancer

Mutant ATRX: pathogenesis of ATRX syndrome and cancer

The transcriptional regulator ATRX, a genetic factor, is associated with a range of disabilities, including intellectual, hematopoietic, skeletal, facial, and urogenital disabilities. ATRX mutations substantially contribute to the pathogenesis of ATRX syndrome and are frequently detected in gliomas...

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Bibliographic Details
Main Authors: Kejia Yuan, Yan Tang, Zexian Ding, Lei Peng, Jinghua Zeng, Huaying Wu, Qi Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
ATRX
ATRX syndrome
replication stress
ALT
transcriptional regulation
tumorigenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1434398/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2024.1434398/full

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