Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis

Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis

Abstract Background Aortic stenosis (AS) is one of the most common cardiac diseases and major cause of morbidity and mortality in the elderly. Transcatheter aortic valve implantation (TAVI) is performed in such patients with symptomatic severe AS and reduces mortality for the majority of these patie...

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Bibliographic Details
Main Authors: Leon Kanwischer, Xingbo Xu, Afifa Binta Saifuddin, Sabine Maamari, Xiaoying Tan, Fouzi Alnour, Björn Tampe, Thomas Meyer, Michael Zeisberg, Gerd Hasenfuss, Miriam Puls, Elisabeth M. Zeisberg
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Clinical Epigenetics
Subjects:
Aortic stenosis
IRX3
Cardiac fibrosis
Epigenetics
DNA methylation
Biomarker
Online Access:https://doi.org/10.1186/s13148-023-01561-2

Internet

https://doi.org/10.1186/s13148-023-01561-2

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