Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy

Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy

<p>Abstract</p> <p>Background</p> <p>We have reported that doxycycline-induced over-expression of wild type prion protein (PrP) in skeletal muscles of Tg(HQK) mice is sufficient to cause a primary myopathy with no signs of peripheral neuropathy. The preferential accumul...

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Bibliographic Details
Main Authors: Wang Meiling, Huang Shenghai, Landry Laura, Sorensen Garrett, Medina Sarah, Parchaliuk Debra, Liang Jingjing, Kong Qingzhong, Booth Stephanie A
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/201

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http://www.biomedcentral.com/1471-2164/10/201

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