Higher mitochondrial oxidative capacity is the primary molecular differentiator in muscle of rats with high and low intrinsic cardiorespiratory fitness

Objective: Cardiorespiratory fitness (CRF) is tightly linked with health and longevity and is implicated in metabolic flexibility and substrate metabolism. The high capacity runner (HCR) and low capacity runner (LCR) rat lines are a genetically heterogeneous rat model selected and bred for CRF that...

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Bibliographic Details
Main Authors: Johanna Y. Fleischman, Françoise Van den Bergh, Nicole L. Collins, Madelyn Bowers, Daniel A. Beard, Charles F. Burant
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823001278