The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput

The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput

Abstract Background Tracking and understanding artemisinin resistance is key for preventing global setbacks in malaria eradication efforts. The ring-stage survival assay (RSA) is the current gold standard for in vitro artemisinin resistance phenotyping. However, the RSA has several drawbacks: it is...

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Bibliographic Details
Main Authors: Sage Z. Davis, Puspendra P. Singh, Katelyn M. Vendrely, Douglas A. Shoue, Lisa A. Checkley, Marina McDew-White, Katrina A. Button-Simons, Zione Cassady, Mackenzie A. C. Sievert, Gabriel J. Foster, François H. Nosten, Timothy J. C. Anderson, Michael T. Ferdig
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Malaria Journal
Subjects:
Ring-stage survival assay
Artemisinin resistance
kelch13
Online Access:https://doi.org/10.1186/s12936-020-3139-6

Internet

https://doi.org/10.1186/s12936-020-3139-6

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