Characterization of a Preclinical In Vitro Model Derived from a SMARCA4-Mutated Sinonasal Teratocarcinosarcoma

Characterization of a Preclinical In Vitro Model Derived from a SMARCA4-Mutated Sinonasal Teratocarcinosarcoma

Sinonasal teratocarcinosarcoma (TCS) is a rare tumor that displays a variable histology with admixtures of epithelial, mesenchymal, neuroendocrine and germ cell elements. Facing a very poor prognosis, patients with TCS are in need of new options for treatment. Recently identified recurrent mutations...

Full description

Bibliographic Details
Main Authors: Sara Lucila Lorenzo-Guerra, Helena Codina-Martínez, Laura Suárez-Fernández, Virginia N. Cabal, Rocío García-Marín, Cristina Riobello, Blanca Vivanco, Verónica Blanco-Lorenzo, Paula Sánchez-Fernández, Fernando López, Jóse Luis Llorente, Mario A. Hermsen
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cells
Subjects:
sinonasal cancer
teratocarcinosarcoma
in vitro model
exome sequencing
SMARCA4 mutation
preclinical drug testing
Online Access:https://www.mdpi.com/2073-4409/13/1/81

Internet

https://www.mdpi.com/2073-4409/13/1/81

Similar Items