Electroacupuncture induces weight loss by regulating tuberous sclerosis complex 1-mammalian target of rapamycin methylation and hypothalamic autophagy in high-fat diet-induced obese rats

Electroacupuncture induces weight loss by regulating tuberous sclerosis complex 1-mammalian target of rapamycin methylation and hypothalamic autophagy in high-fat diet-induced obese rats

Background: Obesity can be caused by abnormalities of hypothalamic autophagy, which is closely regulated by the epigenetic modification of TSC1-mTOR. However, whether the weight-reducing effect of EA may relate to the modification of TSC1-mTOR methylation and hypothalamic autophagy remain unclear. T...

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Bibliographic Details
Main Authors:	Junpeng Yao, Xiangyun Yan, Xianjun Xiao, Xi You, Yanqiu Li, Yuqing Yang, Wei Zhang, Ying Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Series:	Frontiers in Pharmacology
Subjects:	electroacupuncture obesity methylation tuberous sclerosis complex 1 mammalian target of rapamycin autophagy
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1015784/full

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