African genetic ancestry is associated with lower frequency of PNPLA3 G allele in non-alcoholic fatty liver in an admixed population

African genetic ancestry is associated with lower frequency of PNPLA3 G allele in non-alcoholic fatty liver in an admixed population

Introduction and objectives: PNPLA3 (rs738409) and TM6SF2 (rs58542926) variants, interindividual and ethnic differences may be risk factors for non-alcoholic fatty liver disease (NAFLD). The PNPLA3 G allele is associated with worse NAFLD evolution in Hispanics and Caucasians. TM6SF2 is associated wi...

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Bibliographic Details
Main Authors: Lourianne Nascimento Cavalcante, Jun Porto, Daniel Mazo, Adhemar Longatto-Filho, José Tadeu Stefano, Andre Castro Lyra, Flair Jose Carrilho, Rui Manuel Reis, Venâncio A.F. Alves, Arun J. Sanyal, Claudia P Oliveira
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Annals of Hepatology
Subjects:
Steatohepatitis
NASH
Ancestry
PNPLA3
TM62SF
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268122000709

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http://www.sciencedirect.com/science/article/pii/S1665268122000709

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