Inhibition of Mitochondrial Uncoupling Proteins Arrests Human Spermatozoa Motility without Compromising Viability

Inhibition of Mitochondrial Uncoupling Proteins Arrests Human Spermatozoa Motility without Compromising Viability

Mitochondrial uncoupling proteins (UCPs) are central in the regulation of mitochondrial activity and reactive oxygen species (ROS) production. High oxidative stress is a major cause of male infertility; however, UCPs expression and function in human spermatozoa are still unknown. Herein, we aimed to...

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Bibliographic Details
Main Authors: David F. Carrageta, Laís Freire-Brito, Bárbara Guerra-Carvalho, João C. Ribeiro, Bruno S. Monteiro, Alberto Barros, Pedro F. Oliveira, Mariana P. Monteiro, Marco G. Alves
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
genipin
mitochondria
mitochondrial uncoupling proteins
motility
oxidative stress
spermatozoa
Online Access:https://www.mdpi.com/2076-3921/12/2/409

Internet

https://www.mdpi.com/2076-3921/12/2/409

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