Leptomeningeal metastatic cells adopt two phenotypic states

Leptomeningeal metastatic cells adopt two phenotypic states

Abstract Background Leptomeningeal metastasis (LM), or spread of cancer cells into the cerebrospinal fluid (CSF), is characterized by a rapid onset of debilitating neurological symptoms and markedly bleak prognosis. The lack of reproducible in vitro and in vivo models has prevented the development o...

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Bibliographic Details
Main Authors: Jan Remsik, Yudan Chi, Xinran Tong, Ugur Sener, Camille Derderian, Abigail Park, Fadi Saadeh, Tejus Bale, Adrienne Boire
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Cancer Reports
Subjects:
cancer plasticity
cerebrospinal fluid
electron transport chain
leptomeningeal metastasis
metabolic adaptation
Online Access:https://doi.org/10.1002/cnr2.1236

Internet

https://doi.org/10.1002/cnr2.1236

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