Tezacaftor/Ivacaftor therapy has negligible effects on the cystic fibrosis gut microbiome

Tezacaftor/Ivacaftor therapy has negligible effects on the cystic fibrosis gut microbiome

ABSTRACT People with cystic fibrosis (pwCF) experience a range of persistent gastrointestinal symptoms throughout life. There is evidence indicating interaction between the microbiota and gut pathophysiology in CF. However, there is a paucity of knowledge on the potential effects of CF transmembrane...

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Bibliographic Details
Main Authors: Ryan Marsh, Claudio Dos Santos, Liam Hanson, Christabella Ng, Giles Major, Alan R. Smyth, Damian Rivett, Christopher van der Gast
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
gut microbiome
gut microbiota
dysbiosis
CFTR modulator therapy
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01175-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01175-23

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