Mutation of gdpS gene induces a viable but non-culturable state in Staphylococcus epidermidis and changes in the global transcriptional profile

Abstract Background In the genome of staphylococci, only the gdpS gene encodes the conserved GGDEF domain, which is the characteristic of diguanylate cyclases. In our previous study, we have demonstrated that the gdpS gene can modulate biofilm formation by positively regulating the expression of ica...

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Bibliographic Details
Main Authors: Tao Zhu, Wei Wang, Han Wang, Yanfeng Zhao, Di Qu, Yang Wu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-022-02708-6